Research and Clinical Trials

Doctors and scientists in the Craniofacial Center are working to find the causes of craniofacial conditions. We also develop new ways to diagnose and treat these conditions.

Research teams at Seattle Children’s bring together experts from many fields. This gives us the best chance to make new discoveries that might benefit your child.

Cleft Lip and Palate Research

We study  and participate in many local and national studies cleft lip and palate.

Current research focuses on:

  • Measuring results of treatment for clefting.
  • Ways to monitor a baby’s health and growth during the first year.
  • Obstructive sleep apnea in babies with Robin sequence.

Learn more about research on cleft lip and palate at Seattle Children’s.

Our researchers are working to:

  • Create a library of 3-D images to better measure the results of surgery.
  • Understand how craniosynostosis affects learning, attention and behavior.

Learn more about craniosynostosis research at Seattle Children’s.

Research for Children and Families of Children with Undersized Jaws and Ears (Craniofacial Microsomia and Microtia)

Our researchers are studying craniofacial microsomia (CFM) and microtia (small, atypically shaped ears).

We work to:

  • Standardize how CFM is classified and treated.
  • Find genetic and environmental factors that cause undersized ears.

FACIAL National Research Network

Seattle Children’s doctors helped start a national research network focused on CFM. Our goals are to:

  • Compare results of treatment for children with this condition.
  • Develop standards to guide care.

The network is called the Facial Asymmetry Collaborative for Interdisciplinary Analysis and Learning (FACIAL).

Learn more about work with FACIAL in the Heike lab.

CORE Research Team

The Craniofacial Outcomes Research and Epidemiology and Etiology (CORE) group connects many researchers at Seattle Children's. They work together to better understand craniofacial conditions and improve healthcare for patients and families.

Investigators draw on each other’s expertise. Their fields range from epidemiology to genetics to psychology and well-being.

CORE also helps researchers design and carry out studies.

Participate in Research

What we learn from our families in clinic helps our research. Likewise, our research helps us provide the most effective care to your family.

The close link between our clinical and research efforts helps make Seattle Children's a leader in treating craniofacial conditions.

Learn about how and why to participate in research or clinical trials.

Ways to Help

Private donations help our researchers launch studies that could lead to lifesaving treatments. Email us to learn about supporting the Craniofacial Center’s research.